Brain, Mood & Sleep
Compounds reported to influence focus, mood, anxiety, neuroprotection and sleep.
Semax: A Russian Brain Peptide With Strong Animal Data and Thin Human Proof
Semax boosts BDNF and modulates dopamine and serotonin in rodents, but human evidence is small, Russian-only, and mostly stroke-focused — not nootropic.
Selank: A Calm-Without-Sedation Peptide With a Russian Evidence Base
A plain-English look at Selank, the tuftsin-derived anxiolytic peptide: how it works, what the (largely Russian) research shows, doses studied, and honest limits.
Melatonin: A Clock-Setter, Not a Sledgehammer
Melatonin is strong evidence for jet lag and circadian disorders but only modest for adult insomnia — timing matters more than dose.
DSIP: The "Sleep Peptide" That Never Quite Proved Itself
A clear-eyed look at delta sleep-inducing peptide (DSIP): old, contradictory human data, an unknown mechanism, no modern trials, and why the evidence stays weak.